2026-03-11T07:12:24Z https://gifu-pu.repo.nii.ac.jp/oai

oai:gifu-pu.repo.nii.ac.jp:00014850 2023-06-19T07:38:46Z 212:249:345

Electrochemical and Computational Analysis of Superoxide/Hydroperoxyl Radical Trap by 5,5-Dimethyl-1-pyrroline N-oxide in N,N-dimethylformamide Electrochemical and Computational Analysis of Superoxide/Hydroperoxyl Radical Trap by 5,5-Dimethyl-1-pyrroline N-oxide in N,N-dimethylformamide nakayama, tatsushi metadata only access superoxide radical anion hydroperoxyl radical spin trap 5,5-dimethyl-1- pyrroline N-oxide electrochemistry electron spin resonance superoxide radical anion hydroperoxyl radical spin trap 5,5-dimethyl-1- pyrroline N-oxide electrochemistry electron spin resonance Spin trap of electrogenerated superoxide radical anion (O2•−) and hydroperoxyl radical (HO2•) using 5,5-dimethyl-1-pyrroline N-oxide (DMPO) was investigated via cyclicvoltammetry and in situ electrolytic electron spin resonance (ESR) measurements in dehydrated N,Ndimethylformamide (DMF) aided by density functional theory calculations. In aprotic environments, DMPO gradually traps the electrogenerated O2•, however, its trap rate is considerably slow. Conversely, adding a small amount of proton source to O2•− to form HO2• changes the voltammetric behavior, rendering the detection of the spin adduct easy with ESR. These electrochemical and ESR results obtained in aprotic DMF well demonstrate the differences between O2•− trap and HO2• trap, since the effects of a proton derived from aqueous solvent on O2•−/HO2• traps, such as superoxide spontaneous dismutation and pH of solution, are not involved. Accordingly, the obtained kinetic and thermodynamic results show the exact chemical reaction parameters for each of the O2•−/HO2• trap. Therefore, these results will be useful for estimating an apparent O2•−/HO2• adduct-formation in aqueous ESR measurements. IJISET.COM 2022-01-20 jpn article https://gifu-pu.repo.nii.ac.jp/records/14850 2348-7968 International Journal of Innovative Science, Engineering & Technology International Journal of Innovative Science, Engineering & Technology 9 1