{"created":"2023-06-19T07:25:21.631384+00:00","id":13117,"links":{},"metadata":{"_buckets":{"deposit":"6ee66fe4-3c58-4369-932b-cad89132b02b"},"_deposit":{"created_by":24,"id":"13117","owners":[24],"pid":{"revision_id":0,"type":"depid","value":"13117"},"status":"published"},"_oai":{"id":"oai:gifu-pu.repo.nii.ac.jp:00013117","sets":["212:253:333"]},"author_link":["18466","18465","18463","18467","18462","18468","18464"],"item_3_biblio_info_3":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"119","bibliographicPageStart":"113","bibliographicVolumeNumber":"13","bibliographic_titles":[{"bibliographic_title":"Asian Journal of Pharmaceutical Sciences"}]}]},"item_3_text_4":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_text_value":"10.1016/j.ajps.2017.08.002"}]},"item_3_textarea_2":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_textarea_value":"We previously determined “Tableting properties” by using a multi-functional single-punch tablet press (GTP-1). We plotted “Compactability” on the x-axis against “Manufacturability” on the y-axis to allow visual evaluation of “Tableting properties”. Here, we examined whether this evaluation method can be used in the formulation design of tablets prepared by wet granulation. We used the GTP-1 to measure “Tableting properties” with different amounts of binder, disintegrant, and lubricant, and compared the results with those of tableting on a commercial rotary tableting machine. Tableting failures (capping and binding in particular) occurred when samples that had been evaluated as having poor “Compactability” or “Manufacturability” on the GTP-1 were compressed on the rotary tableting machine. Thus, our evaluation method predicted tableting failure at the commercial scale. The method will prove useful for scaling up production."}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"tableting","subitem_subject_scheme":"Other"},{"subitem_subject":"formulation design","subitem_subject_scheme":"Other"},{"subitem_subject":"wet granulation","subitem_subject_scheme":"Other"},{"subitem_subject":"capping","subitem_subject_scheme":"Other"},{"subitem_subject":"binding","subitem_subject_scheme":"Other"},{"subitem_subject":"single-punch tablet press","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Formulation design of granules prepared by wet granulation method using a multi-functional single-punch tablet press to avoid tableting failures","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Formulation design of granules prepared by wet granulation method using a multi-functional single-punch tablet press to avoid tableting failures"}]},"item_type_id":"3","owner":"24","path":["333"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-08-10"},"publish_date":"2017-08-10","publish_status":"0","recid":"13117","relation_version_is_last":true,"title":["Formulation design of granules prepared by wet granulation method using a multi-functional single-punch tablet press to avoid tableting failures"],"weko_creator_id":"24","weko_shared_id":-1},"updated":"2023-06-19T08:58:18.739212+00:00"}