{"created":"2023-06-19T07:25:25.248633+00:00","id":13214,"links":{},"metadata":{"_buckets":{"deposit":"740b707c-3620-4daa-a5ca-f7294b0e2b39"},"_deposit":{"created_by":37,"id":"13214","owners":[37],"pid":{"revision_id":0,"type":"depid","value":"13214"},"status":"published"},"_oai":{"id":"oai:gifu-pu.repo.nii.ac.jp:00013214","sets":["212:254:330"]},"author_link":["19100","18582","18586","19102","18581"],"item_3_biblio_info_3":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"306","bibliographicPageStart":"303","bibliographicVolumeNumber":"30","bibliographic_titles":[{},{"bibliographic_title":"J. Photopolym. Sci. Technol.","bibliographic_titleLang":"en"}]}]},"item_3_text_4":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_text_value":"10.2494/photopolymer.30.303"}]},"item_3_textarea_2":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_textarea_value":"A methacrylic-type polymerizable derivative of naproxen (NP), planned as a prodrug, was directly synthesized from the reaction between 2-hydroxyethyl methacrylate (HEMA) and NP by the esterification method. Then, the polymeric prodrugs containing NP pendent groups were synthesized by the free radical polymerization on plasma irradiated pharmaceutical excipient powders. Hydrolysis of the polymeric prodrugs was carried out in conditions similar to physiological conditions and the results showed that the studied polymeric prodrugs in the present investigation can be used as carriers in controlled drug release, to meet the need for prolonged and better control of drug administration."}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Plasma irradiation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Drug delivery system","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Cellulose derivatives","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Polymeric prodrugs","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Preparation and Characterization of Polymeric Prodrugs of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) by Cold Plasma Technique","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Preparation and Characterization of Polymeric Prodrugs of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) by Cold Plasma Technique"}]},"item_type_id":"3","owner":"37","path":["330"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-05-12"},"publish_date":"2017-05-12","publish_status":"0","recid":"13214","relation_version_is_last":true,"title":["Preparation and Characterization of Polymeric Prodrugs of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) by Cold Plasma Technique"],"weko_creator_id":"37","weko_shared_id":-1},"updated":"2023-06-19T08:58:06.814230+00:00"}