{"created":"2023-06-19T07:25:26.426519+00:00","id":13245,"links":{},"metadata":{"_buckets":{"deposit":"ec6c24c5-4fe8-4ebd-bb76-c87f86c54bd4"},"_deposit":{"created_by":20,"id":"13245","owners":[20],"pid":{"revision_id":0,"type":"depid","value":"13245"},"status":"published"},"_oai":{"id":"oai:gifu-pu.repo.nii.ac.jp:00013245","sets":["212:260:312"]},"author_link":["19332","19338","19336","19333","19335","19334","19337"],"item_3_biblio_info_3":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"11","bibliographicPageEnd":"653","bibliographicPageStart":"648","bibliographicVolumeNumber":"43","bibliographic_titles":[{"bibliographic_title":"医療薬学"}]}]},"item_3_textarea_2":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_textarea_value":"The administration of tazobactam/piperacillin (TAZ/PIPC) to patients with renal failure requires dose reduction since it is eliminated through the kidneys. Therefore, we set TAZ/PIPC dose reduction criteria for the administration of TAZ/PIPC to renal failure patients, in addition, pharmacist checked renal function and dose for proper use. We investigated the influence of the rate of renal failure patients administered TAZ/PIPC on antimicrobial use density (AUD), days of therapy (DOT), and AUD/DOT.\n\tThe rate of the number of patients administered TAZ/PIPC with renal failure, the rate of TAZ/PIPC dose and dosing days were calculated, and these variables were determined for each month of the study period. Furthermore, we assessed the correlations of AUD, DOT, AUD/DOT with patients rate, dose rate and dosing days rate for each month. As a result, AUD/DOT was significantly and negatively correlated with patients rete (r = -0.634, P = 0.027), dose rate (r = -0.783, P = 0.003), and dosing days rate (r = -0.695, P = 0.012).\n\tAUD/DOT is an indicator of the one-day dosing of antimicrobials. TAZ/PIPC one-day dose was accorded with renal function in 84.4% of cases owing to the dose reduction criteria and checked by the pharmacist in this study. This suggests that the dose of TAZ/PIPC was appropriately adjusted based on renal function. We found that as the rate of administration of TAZ/PIPC, eliminated through the kidneys, in patients with renal failure increased, AUD/DOT decreased. Our findings support the appropriate assessment of antimicrobial dosage surveillance.\n"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"tazobactam/piperacillin (TAZ/PIPC), renal function, surveillance, antimicrobial use density (AUD), days of therapy (DOT)","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"腎機能低下患者へのtazobactam/piperacillinの投与が使用量サーベイランスに与える影響","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"腎機能低下患者へのtazobactam/piperacillinの投与が使用量サーベイランスに与える影響"},{"subitem_title":"Influence of dosages surveillance on the administration of tazobactam/piperacillin to patients with renal failure","subitem_title_language":"en"}]},"item_type_id":"3","owner":"20","path":["312"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-06-15"},"publish_date":"2018-06-15","publish_status":"0","recid":"13245","relation_version_is_last":true,"title":["腎機能低下患者へのtazobactam/piperacillinの投与が使用量サーベイランスに与える影響"],"weko_creator_id":"20","weko_shared_id":-1},"updated":"2023-06-19T08:57:58.563281+00:00"}