{"created":"2023-06-19T07:25:27.852497+00:00","id":13287,"links":{},"metadata":{"_buckets":{"deposit":"65b401d7-4823-4492-802a-29f8470da168"},"_deposit":{"created_by":47,"id":"13287","owners":[47],"pid":{"revision_id":0,"type":"depid","value":"13287"},"status":"published"},"_oai":{"id":"oai:gifu-pu.repo.nii.ac.jp:00013287","sets":["212:262:306"]},"author_link":["19699","19696","19700","19701","19694","19697","19695","19698","19693"],"item_3_biblio_info_3":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-05-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"299","bibliographicPageStart":"296","bibliographicVolumeNumber":"72","bibliographic_titles":[{},{"bibliographic_title":"Die Pharmazie","bibliographic_titleLang":"en"}]}]},"item_3_text_4":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_text_value":"10.1691/ph.2017.6968"}]},"item_3_textarea_2":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_textarea_value":"We implemented an antimicrobial stewardship (AS) program whereby pharmacists sought appropriate use of antimicrobial agents in January 2012. At that time, we targeted anti-methicillin-resistant Staphylococcus aureus (MRSA) agents and carbapenems; however, in January 2014, we added tazobactam/piperacillin (TAZ/PIPC). We evaluated outcomes using multilateral analyses. The average one-day dosage of carbapenems increased; however, the duration of administration and number of recipient patients decreased significantly (P < 0.01). Moreover, the percentage of patients receiving meropenem (MEPM), for whom the time above minimal inhibitory concentration (MIC) was 40% or higher increased (P < 0.01). In contrast, patient utilization of TAZ/PIPC increased significantly after targeting of carbapenems as specific antibacterial agents. However, after TAZ/PIPC was targeted as a specific antibacterial agent, the number of TAZ/PIPC administrations decreased significantly (P < 0.01). The duration of hospitalization and mortality rate in patients receiving specific antibacterial agents significantly decreased after implementation of the AS program (P < 0.01). In conclusion, pharmacist's interventions to provide AS and patient follow-up reduced improper use and promoted proper administration of antibacterial agents. Furthermore, AS was effective in improving patient prognoses and suppressing drug-resistant strains, as well as promoting effective treatment."}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Evaluation of antimicrobial stewardship (AS) for appropriate use of antimicrobial agents.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Evaluation of antimicrobial stewardship (AS) for appropriate use of antimicrobial agents.","subitem_title_language":"en"}]},"item_type_id":"3","owner":"47","path":["306"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-07-06"},"publish_date":"2018-07-06","publish_status":"0","recid":"13287","relation_version_is_last":true,"title":["Evaluation of antimicrobial stewardship (AS) for appropriate use of antimicrobial agents."],"weko_creator_id":"47","weko_shared_id":-1},"updated":"2023-06-19T08:57:22.533524+00:00"}