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Early cure of Mycobacterium abscessus tunnel infection while maintaining peritoneal dialysis through a combination of antibiotic treatment and catheter replacement
https://gifu-pu.repo.nii.ac.jp/records/13715
https://gifu-pu.repo.nii.ac.jp/records/1371582744f75-b32f-4a03-b0cc-01b50dc3b323
| Item type | 研究室原著論文(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2020-03-04 | |||||
| タイトル | ||||||
| タイトル | Early cure of Mycobacterium abscessus tunnel infection while maintaining peritoneal dialysis through a combination of antibiotic treatment and catheter replacement | |||||
| タイトル | ||||||
| タイトル | Early cure of Mycobacterium abscessus tunnel infection while maintaining peritoneal dialysis through a combination of antibiotic treatment and catheter replacement | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | peritoneal dialysis | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | mycobacterium abscessus | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | tunnel infection | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | amikacin | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | antibiotics | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | pharmacokinetic | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | drug-resistance | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 抄録 | ||||||
| 値 | Mycobacterium abscessusis a rare but important bacterium involved in tunnel infection in patients on peritonealdialysis.TunnelinfectionbyMycobacteriumabscessusisrefractoryandeasilyrecurs, becoming a factor for cessation of peritoneal dialysis. We report a case in which tunnel infection by Mycobacterium abscessus, which recurred after outpatient antibiotic therapy, was successfully cured by combination antibiotic therapy and replacement of the peritoneal dialysis catheter. A 50-year-old man had undergone peritoneal dialysis since the age of 48 years. Mycobacterium abscessuswas detected in pus attheperitonealdialysisoutlet,andhewasdiagnosedwithtunnelinfection.Weadministered clarithromycin monotherapy twice in the outpatient setting based on susceptibility; however, owing to relapse,thepatientwashospitalized.Thereafter,amikacinwasadministeredinadditionto clarithromycin. Subsequently, linezolid and imipenem/cilastatin were also used in combination while monitoring blood concentration and side effects. The peritoneal dialysis catheter was removed on day 16 after hospitalization, and reinserted on day 23. During period of 7 days, the patient's urination and creatinine level was stable. The tunnel infection was cured 40 days from hospitalization, and there was no deterioration in kidney function during treatment. Thereafter, there was no relapse for 400 days, and reduced residual renal function and coagulase negative staphylococcus peritonitis caused shift to hemodialysis. This case demonstrates that both short-term combination antibiotic therapy at the beginning of antimicrobial drug administration and catheter replacement are important for short-term treatment while continuing peritoneal dialysis. | |||||
| 書誌情報 |
Open Journal of Clinical and Medical Case Reports en : Open Journal of Clinical and Medical Case Reports 巻 4, 発行日 2019 |
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| DOI | ||||||
| 値 | http://jclinmedcasereports.com/articles/OJCMCR-1473.pdf | |||||
