Changes in the quality of medicines during storage under LED lighting and consideration of countermeasures

インデックスリンク

インデックスツリー

RootNode

アイテム

Changes in the quality of medicines during storage under LED lighting and consideration of countermeasures

https://gifu-pu.repo.nii.ac.jp/records/13716

Item type		研究室原著論文(1)
公開日		2020-03-04
タイトル
	タイトル	Changes in the quality of medicines during storage under LED lighting and consideration of countermeasures
タイトル
	タイトル	Changes in the quality of medicines during storage under LED lighting and consideration of countermeasures
	言語	en
言語
	言語	eng
キーワード
	言語	en
	主題Scheme	Other
	主題	Color change
キーワード
	言語	en
	主題Scheme	Other
	主題	Fluorescent lighting
キーワード
	言語	en
	主題Scheme	Other
	主題	LED lighting
キーワード
	言語	en
	主題Scheme	Other
	主題	Medicines
キーワード
	言語	en
	主題Scheme	Other
	主題	Photostability
資源タイプ
	資源タイプ識別子	http://purl.org/coar/resource_type/c_6501
	資源タイプ	journal article
アクセス権
	アクセス権	metadata only access
	アクセス権URI	http://purl.org/coar/access_right/c_14cb
抄録
	値	BACKGROUND: In recent years, the popularity of LED lighting has rapidly increased, owing to its many advantages, including economic benefits. We examined the change in the quality of drugs during storage under LED and fluorescent lighting and found that some medicines exhibited a different degree of color change depending on the light source. The purpose of this study was to investigate the effects of different plastic storage bags on the color change over time when various medicines were stored under LED and fluorescent lighting conditions. METHODS: Photostability tests were conducted on several types of target drugs. Subsequently, subjective evaluation by ten evaluators and objective evaluation by image analysis software were carried out regarding color change. RESULTS: A similar change in color tone was observed after all types of illumination. Subjective evaluation by 10 evaluators revealed that "change in color tone" occurred in the order of bulb-color LED lighting < daylight-color LED lighting < fluorescent lighting, regardless of the type of plastic bags. A similar tendency was observed also in objective evaluation. In this study, it was considered that a brown light-shielding plastic bag was more effective than a normal plastic bag for the prevention of the color change of medicines stored under LED lighting. CONCLUSIONS: The above results suggested that the most appropriate combination of plastic bag and light source for medicine storage was a brown light-shielding plastic bag and bulb-color LED lighting.
書誌情報		en : Journal of Pharmaceutical Health Care and Sciences 巻 4, 号 1, 発行日 2018
DOI
	値	10.1186/s40780-018-0108-0