{"created":"2023-06-19T07:25:42.937218+00:00","id":13751,"links":{},"metadata":{"_buckets":{"deposit":"88b70b3a-20db-400d-90dc-37223e9767fa"},"_deposit":{"created_by":40,"id":"13751","owners":[40],"pid":{"revision_id":0,"type":"depid","value":"13751"},"status":"published"},"_oai":{"id":"oai:gifu-pu.repo.nii.ac.jp:00013751","sets":["212:271:294"]},"author_link":["29386","29384","29385","29388","29387"],"item_3_biblio_info_3":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-10","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"89","bibliographicPageStart":"87","bibliographicVolumeNumber":"77","bibliographic_titles":[{},{"bibliographic_title":"International Journal of Infectious Diseases","bibliographic_titleLang":"en"}]}]},"item_3_text_4":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_text_value":"10.1016/j.ijid.2018.10.006"}]},"item_3_textarea_2":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_textarea_value":"A 27-year-old pregnant woman who was positive for anti-cytomegalovirus (CMV) antibodies gave birth to a congenitally CMV-infected neonate at 40 weeks of gestation. According to strain-specific serological analysis, which is able to determine the two types of CMV glycoprotein H (gH), the mother possessed anti-gH(To) antibodies only, but the neonate possessed anti-gH(AD) and anti-gH(To) antibodies at 4 weeks after birth. As the anti-gH(To) IgG was decreased in the neonate at 8 months post-delivery, these antibodies are thought to have been transferred from the mother as maternal antibodies. The anti-gH(AD) IgG level was maintained in the child even after 8 months post-delivery. Congenital infection with a CMV gH(AD) type strain was confirmed by strain-specific real-time PCR using a urine specimen from the child. On the other hand, anti-gH(AD) IgG was not detected even after 8 months post-delivery in a maternal specimen. The mother only produced antibodies against the CMV strain identified as the primary infection, which is characteristic of original antigenic sin."}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Cytomegalovirus","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Congenital infection","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Glycoprotein H","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Original antigenic sin","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Congenital cytomegalovirus infection via a re-infected mother with original antigenic sin: A case report","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Congenital cytomegalovirus infection via a re-infected mother with original antigenic sin: A case report","subitem_title_language":"en"}]},"item_type_id":"3","owner":"40","path":["294"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-03-04"},"publish_date":"2020-03-04","publish_status":"0","recid":"13751","relation_version_is_last":true,"title":["Congenital cytomegalovirus infection via a re-infected mother with original antigenic sin: A case report"],"weko_creator_id":"40","weko_shared_id":-1},"updated":"2023-06-19T07:49:33.592909+00:00"}