{"created":"2023-06-19T07:26:06.941068+00:00","id":14387,"links":{},"metadata":{"_buckets":{"deposit":"be9e5832-5cee-4862-a787-bd9049e8b238"},"_deposit":{"created_by":16,"id":"14387","owners":[16],"pid":{"revision_id":0,"type":"depid","value":"14387"},"status":"published"},"_oai":{"id":"oai:gifu-pu.repo.nii.ac.jp:00014387","sets":["212:257:321"]},"author_link":["33606","33604","33603","33605"],"item_3_biblio_info_3":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"11","bibliographicPageEnd":"2447","bibliographicPageStart":"2442","bibliographicVolumeNumber":"19","bibliographic_titles":[{},{"bibliographic_title":"Organic & Biomolecular Chemistry","bibliographic_titleLang":"en"}]}]},"item_3_textarea_2":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_textarea_value":"The stereoselective synthesis of cis-β-N-alkoxyamidevinyl benziodoxolones (cis-β-N-RO-amide-VBXs) I (R = 4-iodophenyl, cyclopropyl, pyridin-3-yl, etc.) from O-alkyl hydroxamic acids RC(O)NHOCH3 in the presence of an ethynyl benziodoxolone-acetonitrile complex (EBX-MeCN) is reported herein. The reaction was performed under mild conditions including an aqueous solvent, a mild base, and room temperature The reaction tolerated various O-alkyl hydroxamic acids derived from carboxylic acids, such as amino acids, pharmaceuticals, and natural products. Vinyl dideuterated cis-β-N-MeO-amide-VBXs, e.g., II, were also synthesized using deuterium oxide as the deuterium source. Valine-derived cis-β-N-MeO-amide-VBX was stereospecifically derivatized to hydroxamic acid-derived cis-enamides, e.g., III, without the loss of stereoselectivity or reduction in the deuterium/hydrogen ratio."}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"N-Alkenylation of hydroxamic acid derivatives with ethynyl benziodoxolone to synthesize cis-enamides through vinyl benziodoxolones","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"N-Alkenylation of hydroxamic acid derivatives with ethynyl benziodoxolone to synthesize cis-enamides through vinyl benziodoxolones"},{"subitem_title":"N-Alkenylation of hydroxamic acid derivatives with ethynyl benziodoxolone to synthesize cis-enamides through vinyl benziodoxolones","subitem_title_language":"en"}]},"item_type_id":"3","owner":"16","path":["321"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-03-02"},"publish_date":"2022-03-02","publish_status":"0","recid":"14387","relation_version_is_last":true,"title":["N-Alkenylation of hydroxamic acid derivatives with ethynyl benziodoxolone to synthesize cis-enamides through vinyl benziodoxolones"],"weko_creator_id":"16","weko_shared_id":-1},"updated":"2023-06-19T07:43:19.874123+00:00"}