{"created":"2023-06-19T07:26:11.627398+00:00","id":14519,"links":{},"metadata":{"_buckets":{"deposit":"c1b2afa6-784d-48cb-a55f-6c8e66013772"},"_deposit":{"created_by":139,"id":"14519","owners":[139],"pid":{"revision_id":0,"type":"depid","value":"14519"},"status":"published"},"_oai":{"id":"oai:gifu-pu.repo.nii.ac.jp:00014519","sets":["212:231:232"]},"author_link":["34497","34496","34498","34495"],"item_3_biblio_info_3":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"10","bibliographicPageEnd":"1288","bibliographicPageStart":"1285","bibliographicVolumeNumber":"36","bibliographic_titles":[{},{"bibliographic_title":"Analytical Sciences","bibliographic_titleLang":"en"}]}]},"item_3_text_4":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_text_value":"10.2116/analsci.20N010"}]},"item_3_textarea_2":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_textarea_value":"A highly sensitive high-performance liquid chromatography method has been developed using the pre-column fluorescent derivatization of daptomycin (DAP) through cyclization of the amino group of ornithine with 2,3-naphthalenedialdehyde. With the proposed method, the limits of detection and quantification of DAP in murine serum were 8 and 3 nmol/L, respectively, and the calibration curve was linear across the examined dynamic range from 8 nmol/L to 1 μmol/L (n = 8, r = 0.9986). This method is suitable for animal experiments examining the side effects of DAP therapy using mice as a simple method with quantification to the order of 10 nmol/L."}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Highly Sensitive Fluorescence Detection of Daptomycin in Murine Samples through Derivatization with 2,3-Naphthalenedialdehyde","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Highly Sensitive Fluorescence Detection of Daptomycin in Murine Samples through Derivatization with 2,3-Naphthalenedialdehyde"}]},"item_type_id":"3","owner":"139","path":["232"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-03-06"},"publish_date":"2022-03-06","publish_status":"0","recid":"14519","relation_version_is_last":true,"title":["Highly Sensitive Fluorescence Detection of Daptomycin in Murine Samples through Derivatization with 2,3-Naphthalenedialdehyde"],"weko_creator_id":"139","weko_shared_id":-1},"updated":"2023-06-19T07:42:08.862537+00:00"}