{"created":"2023-06-19T07:26:23.861679+00:00","id":14849,"links":{},"metadata":{"_buckets":{"deposit":"dc00ac14-57bf-4ef5-9e65-441594ef0a3c"},"_deposit":{"created_by":140,"id":"14849","owners":[140],"pid":{"revision_id":0,"type":"depid","value":"14849"},"status":"published"},"_oai":{"id":"oai:gifu-pu.repo.nii.ac.jp:00014849","sets":["212:249:345"]},"author_link":["17923","36611","36612","32440","36610"],"item_10004_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-12-22","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageStart":"9","bibliographicVolumeNumber":"11","bibliographic_titles":[{"bibliographic_title":"antioxidants"},{"bibliographic_title":"antioxidants","bibliographic_titleLang":"en"}]}]},"item_10004_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Scavenging of superoxide radical anion (O2•−) by tocopherols (TOH) and related compounds was investigated on the basis of cyclic voltammetry and in situ electrolytic electron spin resonance spectrum in N,N-dimethylformamide (DMF) with the aid of density functional theory (DFT) calculations. Quasi-reversible dioxygen/O2•− redox was modified by the presence of TOH, suggesting that the electrogenerated O2•− was scavenged by α-, β-, γ-TOH through proton-coupled electron transfer (PCET), but not by δ-TOH. The reactivities of α-, β-, γ-, and δ-TOH toward O2•− characterized by the methyl group on the 6-chromanol ring was experimentally confirmed, where the methyl group promotes the PCET mechanism. Furthermore, comparative analyses using some related compounds suggested that the para-oxygen-atom in the 6-chromanol ring is required for a successful electron transfer (ET) to O2•− through the PCET. The electrochemical and DFT results in dehydrated DMF suggested that the PCET mechanism involves the preceding proton transfer (PT) forming a hydroperoxyl radical, followed by a PCET (intermolecular ET–PT). The O2•− scavenging by TOH proceeds efficiently along the PCET mechanism involving one ET and two PTs.","subitem_description_type":"Abstract"}]},"item_10004_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"MDPI"}]},"item_10004_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"doi.org/10.3390/antiox11010009","subitem_relation_type_select":"DOI"}}]},"item_10004_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2076-3921","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nakayama, Tatsushi"}],"nameIdentifiers":[{"nameIdentifier":"32440","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"N000638361","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/N000638361"}]},{"creatorNames":[{"creatorName":"Honda, Ryo"}],"nameIdentifiers":[{"nameIdentifier":"36610","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kuwata, Kazuo"}],"nameIdentifiers":[{"nameIdentifier":"36611","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Usui, Shigeyuki"}],"nameIdentifiers":[{"nameIdentifier":"36612","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Uno, Bunji"}],"nameIdentifiers":[{"nameIdentifier":"17923","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-03-20"}],"displaytype":"detail","filename":"antioxidants-11-00009.pdf","filesize":[{"value":"3.8 MB"}],"format":"application/pdf","licensetype":"license_6","mimetype":"application/pdf","url":{"label":"https://www.mdpi.com/2076-3921/11/1/9","url":"https://gifu-pu.repo.nii.ac.jp/record/14849/files/antioxidants-11-00009.pdf"},"version_id":"fe960715-6b4c-4e29-9c13-57fed1ea7b1a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"proton-coupled electron transfer","subitem_subject_scheme":"Other"},{"subitem_subject":"superoxide radical anion","subitem_subject_scheme":"Other"},{"subitem_subject":"antioxidants","subitem_subject_scheme":"Other"},{"subitem_subject":"cyclic voltammetry","subitem_subject_scheme":"Other"},{"subitem_subject":"electron spin resonance spectrum","subitem_subject_scheme":"Other"},{"subitem_subject":"tocopherol","subitem_subject_scheme":"Other"},{"subitem_subject":"proton-coupled electron transfer","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"superoxide radical anion","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"antioxidants","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cyclic voltammetry","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"electron spin resonance spectrum","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"tocopherol","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Electrochemical and Mechanistic Study of Reactivities of α-, β-, γ-, and δ-Tocopherol toward Electrogenerated Superoxide in N,N-Dimethylformamide through Proton-Coupled Electron Transfer","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Electrochemical and Mechanistic Study of Reactivities of α-, β-, γ-, and δ-Tocopherol toward Electrogenerated Superoxide in N,N-Dimethylformamide through Proton-Coupled Electron Transfer"},{"subitem_title":"Electrochemical and Mechanistic Study of Reactivities of α-, β-, γ-, and δ-Tocopherol toward Electrogenerated Superoxide in N,N-Dimethylformamide through Proton-Coupled Electron Transfer","subitem_title_language":"en"}]},"item_type_id":"10004","owner":"140","path":["345"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-12-22"},"publish_date":"2021-12-22","publish_status":"0","recid":"14849","relation_version_is_last":true,"title":["Electrochemical and Mechanistic Study of Reactivities of α-, β-, γ-, and δ-Tocopherol toward Electrogenerated Superoxide in N,N-Dimethylformamide through Proton-Coupled Electron Transfer"],"weko_creator_id":"140","weko_shared_id":-1},"updated":"2023-06-19T07:38:47.664059+00:00"}