{"created":"2023-06-19T07:23:58.795653+00:00","id":9079,"links":{},"metadata":{"_buckets":{"deposit":"b641878d-80e9-4366-b61f-8b5e92c7b56f"},"_deposit":{"created_by":5,"id":"9079","owners":[5],"pid":{"revision_id":0,"type":"depid","value":"9079"},"status":"published"},"_oai":{"id":"oai:gifu-pu.repo.nii.ac.jp:00009079","sets":["147:188"]},"author_link":["14087","14088","14086"],"item_1_alternative_title_5":{"attribute_name":"論文名よみ","attribute_value_mlt":[{"subitem_alternative_title":"〓"}]},"item_1_biblio_info_14":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1992-06-30","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"22","bibliographicPageStart":"11","bibliographicVolumeNumber":"41","bibliographic_titles":[{"bibliographic_title":"岐阜藥科大學紀要"},{"bibliographic_title":"The annual proceedings of Gifu College of Pharmacy","bibliographic_titleLang":"en"}]}]},"item_1_creator_6":{"attribute_name":"著者名(日)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"古川, 昭栄"}],"nameIdentifiers":[{"nameIdentifier":"14086","nameIdentifierScheme":"WEKO"}]}]},"item_1_creator_7":{"attribute_name":"著者名よみ","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"フルカワ, ショウエイ"}],"nameIdentifiers":[{"nameIdentifier":"14087","nameIdentifierScheme":"WEKO"}]}]},"item_1_creator_8":{"attribute_name":"著者名(英)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"FURUKAWA, SHOEI","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"14088","nameIdentifierScheme":"WEKO"}]}]},"item_1_description_1":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_type":"Other"}]},"item_1_description_11":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_description":"神経成長因子は118個のアミノ酸からなる塩基性タンパク質である。その作用は特定の神経細胞膜上にある特異的受容体との結合を介して細胞内に伝達されその結果, 神経細胞の分化, 生存を促す。神経成長因子およびそのファミリーは末梢神経系ばかりでなく中枢神経系でも合成され機能していることが近年明らかにされ, アルツハイマー型痴呆症をはじめとする神経変性疾患の治療薬として期待が高まっている。","subitem_description_type":"Other"}]},"item_1_description_12":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"Nerve growth factor (NGF) is a protein that stimulates differentiation and maintains survival of sympathetic, some sensory neurons in the peripheral nervous system and magnocellular cholinergic neurons in the central nervous system. In this article, recent advances in NGF research field are presented as follows : 1) NGF-related molecules (NGF family proteins), 2) trk oncogene family coding high affinity NGF receptor, 3) NGF and NGF family protein potentials for application to degenerative neurological disorder treatment.","subitem_description_type":"Other"}]},"item_1_source_id_13":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AN00053514","subitem_source_identifier_type":"NCID"}]},"item_1_text_10":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Laboratory of Molecular Biology, Gifu Pharmaceutical University"}]},"item_1_text_9":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_value":"岐阜薬科大学"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"1992-06-30"}],"displaytype":"detail","filename":"KJ00000072715.pdf","filesize":[{"value":"1.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"url":"https://gifu-pu.repo.nii.ac.jp/record/9079/files/KJ00000072715.pdf"},"version_id":"2e5ca753-2bb9-4157-af0b-67c7b79c2366"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"<総説>神経成長因子とそのファミリーの構造と機能 : 基礎研究から医学的応用へ","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"<総説>神経成長因子とそのファミリーの構造と機能 : 基礎研究から医学的応用へ"},{"subitem_title":"<Review>Nerve Growth Factor and Related Molecules : Structure, Physiological Functions and Therapeutic Applications","subitem_title_language":"en"}]},"item_type_id":"1","owner":"5","path":["188"],"pubdate":{"attribute_name":"公開日","attribute_value":"1992-06-30"},"publish_date":"1992-06-30","publish_status":"0","recid":"9079","relation_version_is_last":true,"title":["<総説>神経成長因子とそのファミリーの構造と機能 : 基礎研究から医学的応用へ"],"weko_creator_id":"5","weko_shared_id":-1},"updated":"2023-06-19T09:06:58.674373+00:00"}