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Changes in the quality of medicines during storage under LED lighting and consideration of countermeasures.
https://gifu-pu.repo.nii.ac.jp/records/13257
https://gifu-pu.repo.nii.ac.jp/records/132577ba68836-77cb-4927-afa5-cadaa05114e8
Item type | 研究室原著論文(1) | |||||
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公開日 | 2018-06-15 | |||||
タイトル | ||||||
タイトル | Changes in the quality of medicines during storage under LED lighting and consideration of countermeasures. | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | LED lighting | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Fluorescent lighting | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Photostability | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Color change | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Medicines | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
抄録 | ||||||
値 | Background In recent years, the popularity of LED lighting has rapidly increased, owing to its many advantages, including economic benefits. We examined the change in the quality of drugs during storage under LED and fluorescent lighting and found that some medicines exhibited a different degree of color change depending on the light source. The purpose of this study was to investigate the effects of different plastic storage bags on the color change over time when various medicines were stored under LED and fluorescent lighting conditions. Methods Photostability tests were conducted on several types of target drugs. Subsequently, subjective evaluation by ten evaluators and objective evaluation by image analysis software were carried out regarding color change. Results A similar change in color tone was observed after all types of illumination. Subjective evaluation by 10 evaluators revealed that “change in color tone” occurred in the order of bulb-color LED lighting < daylight-color LED lighting < fluorescent lighting, regardless of the type of plastic bags. A similar tendency was observed also in objective evaluation. In this study, it was considered that a brown light-shielding plastic bag was more effective than a normal plastic bag for the prevention of the color change of medicines stored under LED lighting. Conclusions The above results suggested that the most appropriate combination of plastic bag and light source for medicine storage was a brown light-shielding plastic bag and bulb-color LED lighting. |
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書誌情報 |
en : Journal of pharmaceutical health care and sciences 巻 4, p. 12, 発行日 2018-06 |
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DOI | ||||||
値 | 10.1186/s40780-018-0108-0 |