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  1. 教員研究業績
  2. 実践社会薬学研究室
  3. 原著論文

Clinical outcome of pharmacist-led prospective audit with intervention and feedback after expansion from patients using specific antibiotics to those using whole injectable antibiotics

https://gifu-pu.repo.nii.ac.jp/records/13718
https://gifu-pu.repo.nii.ac.jp/records/13718
9fb4f40d-cff8-4871-8a6f-17980b0f1ad8
Item type 研究室原著論文(1)
公開日 2020-03-04
タイトル
タイトル Clinical outcome of pharmacist-led prospective audit with intervention and feedback after expansion from patients using specific antibiotics to those using whole injectable antibiotics
タイトル
タイトル Clinical outcome of pharmacist-led prospective audit with intervention and feedback after expansion from patients using specific antibiotics to those using whole injectable antibiotics
言語 en
言語
言語 eng
キーワード
言語 en
主題Scheme Other
主題 Antimicrobial resistance
キーワード
言語 en
主題Scheme Other
主題 Antimicrobial stewardship
キーワード
言語 en
主題Scheme Other
主題 Intervention
キーワード
言語 en
主題Scheme Other
主題 Japan
キーワード
言語 en
主題Scheme Other
主題 Pharmacist
キーワード
言語 en
主題Scheme Other
主題 Prospective audit with intervention and feedback
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
抄録
値 Prospective audit with intervention and feedback (PAF) and preauthorisation of antimicrobials are core strategies for antimicrobial stewardship (AS). PAF participants were expanded from patients using specific antibiotics to those using whole injectable antibiotics to evaluate clinical outcome. From January 2016 to December 2016, PAF was performed in patients using specific antibiotics (period 1) and from January 2017 to December 2017, PAF was performed in patients using whole injectable antibiotics (period 2). PAF was implemented for 5 days every week by pharmacists involved in infectious diseases chemotherapy. In total, 11,571 and 11,103 patients used antibiotic injections during periods 1 and 2, respectively. No significant difference in mortality within 30 days from the initial use of injection antibiotics was observed. The average duration of hospitalisation was significantly shorter during period 2 among patients using antibiotics; however, this was not significantly different from that of patients not receiving antibiotics. The average duration of therapy for intravenous antibiotics was significantly shorter during period 2 than during period 1. The ratio of methicillin-resistant Staphylococcus aureus (MRSA) to S. aureus was significantly low during period 2. The duration of intravenous antibiotic therapy for Escherichia coli bacteraemia during period 2 decreased significantly. De-escalation and appropriate antimicrobial treatment rates at specific doses during period 2 increased significantly. Expansion of patients eligible for PAF from patients using specific antibiotics to patients using whole injectable antibiotics shortened hospital stays, suppressed drug resistance, and promoted the appropriate use of antibiotics.
書誌情報 en : European Journal of Clinical Microbiology & Infectious Diseases

巻 38, 号 3, p. 593-600, 発行日 2019
DOI
値 10.1007/s10096-018-03465-z
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