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Prodromal Symptoms of Cholinergic Crisis Following Appropriate Administration of Rivastigmine Patch
https://gifu-pu.repo.nii.ac.jp/records/14317
https://gifu-pu.repo.nii.ac.jp/records/143170654ddf6-7282-4a5e-ba06-cd3d3f0fd20b
Item type | 研究室原著論文(1) | |||||
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公開日 | 2021-03-08 | |||||
タイトル | ||||||
タイトル | Prodromal Symptoms of Cholinergic Crisis Following Appropriate Administration of Rivastigmine Patch | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
抄録 | ||||||
値 | Rivastigmine is a cholinesterase inhibitor used in the treatment of Alzheimer‒type dementia. Since rivastigmine patch is a transdermal patch, the incidence of gastrointestinal disorders is lower than that associated with oral administration. Some case reports have reported cholinergic symptoms following the administration of rivastigmine patch, but the administration of rivastigmine patch was inappropriate in these reports. Nowadays, cholinergic symptoms following the appropriate administration of rivastigmine patch are rarely reported. We present a case with prodromal symptoms of cholinergic crisis following appropriate administration of rivastigmine patch. A 67‒year‒old woman with Alzheimer‒type dementia receiving 13.5 mg of rivastigmine patch presented with prodromal symptoms of cholinergic crisis such as nausea, vomiting, and diarrhea with low serum cholinesterase. Rivastigmine patch was removed immediately, and her gastrointestinal disorders were resolved in a day. This case suggests that careful attention to the appearance of prodromal symptoms of cholinergic crisis is important and serum cholinesterase should be checked even in case of appropriate administration of rivastigmine patch. | |||||
書誌情報 |
Therapeutic Research 巻 41, 号 4, p. 355-357 |