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  1. 教員研究業績
  2. 薬物治療学研究室
  3. 原著論文

Evaluation of headaches in primary brain calcification in Japan

https://gifu-pu.repo.nii.ac.jp/records/14565
https://gifu-pu.repo.nii.ac.jp/records/14565
8bd71b0b-cb29-4c9e-99b2-6cbe949961c0
Item type 研究室原著論文(1)
公開日 2022-03-07
タイトル
タイトル Evaluation of headaches in primary brain calcification in Japan
タイトル
タイトル Evaluation of headaches in primary brain calcification in Japan
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
抄録
値 Methods
The first questionnaire survey was conducted on 173 patients diagnosed as having PBC in Japan. Subsequently, the second survey was performed using two types of questionnaire: Headache Impact Test (HIT-6) and Migraine Disability Assessment (MIDAS).

Results
In the first survey, 27 of 82 patients had headaches. Only one patient was able to be classified in accordance with the criteria as having migraine without aura. In the second survey, 10 of 17 patients showed a significant score of 50 and higher in HIT-6, and five of 17 patients showed a significant score of 6 and higher in MIDAS. No significant correlation was found between total calcification score and HIT-6 score or MIDAS score in the second survey. All patients carrying the PDGFB variant and two of three patients carrying the SLC20A2 variant showed some effects of headache on their daily life as judged from their MIDAS scores or HIT-6 score.

Conclusions
The headaches in PBC patients could not be classified as the primary headache. Those headaches in PBC patients may be of the secondary headache caused by the dysfunction of the blood-brain barrier. This first report on headaches of Japanese patients with PBC will contribute to the understanding of PBC patients' difficulties in their daily lives.
書誌情報 en : Neurology and Clinical Neuroscience

巻 9, 号 6, p. 459-465, 発行日 2021
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