{"_buckets": {"deposit": "41ce7589-4fb2-426a-8cbe-13fd5950c7ea"}, "_deposit": {"created_by": 5, "id": "12168", "owners": [5], "pid": {"revision_id": 0, "type": "depid", "value": "12168"}, "status": "published"}, "_oai": {"id": "oai:gifu-pu.repo.nii.ac.jp:00012168", "sets": ["197"]}, "author_link": ["22117", "22124", "17157", "17924", "22120", "22127", "22121", "22118", "17156", "22116", "22115", "17747", "22119", "22122", "22126", "22123", "22125", "17158"], "item_1_alternative_title_5": {"attribute_name": "論文名よみ", "attribute_value_mlt": [{"subitem_alternative_title": "〓"}]}, "item_1_biblio_info_14": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2001-06-30", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "65", "bibliographicPageStart": "61", "bibliographicVolumeNumber": "50", "bibliographic_titles": [{"bibliographic_title": "岐阜藥科大學紀要"}, {"bibliographic_title": "The annual proceedings of Gifu College of Pharmacy", "bibliographic_titleLang": "en"}]}]}, "item_1_creator_6": {"attribute_name": "著者名(日)", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "恋田, 和憲"}], "nameIdentifiers": [{"nameIdentifier": "17156", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "今村, 仁"}], "nameIdentifiers": [{"nameIdentifier": "22115", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "森本, 宏治"}], "nameIdentifiers": [{"nameIdentifier": "22116", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "橋本, 圭二"}], "nameIdentifiers": [{"nameIdentifier": "22117", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "河合, 聡"}], "nameIdentifiers": [{"nameIdentifier": "22118", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "宇野, 文二"}], "nameIdentifiers": [{"nameIdentifier": "17747", "nameIdentifierScheme": "WEKO"}]}]}, "item_1_creator_7": {"attribute_name": "著者名よみ", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "コイダ, カズノリ"}], "nameIdentifiers": [{"nameIdentifier": "17157", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "イマムラ, ヒトシ"}], "nameIdentifiers": [{"nameIdentifier": "22119", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "モリモト, コウジ"}], "nameIdentifiers": [{"nameIdentifier": "22120", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "ハシモト, ケイジ"}], "nameIdentifiers": [{"nameIdentifier": "22121", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "カワイ, サトシ"}], "nameIdentifiers": [{"nameIdentifier": "22122", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "ウノ, ブンジ"}], "nameIdentifiers": [{"nameIdentifier": "22123", "nameIdentifierScheme": "WEKO"}]}]}, "item_1_creator_8": {"attribute_name": "著者名(英)", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "KOIDA, Kazunori", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "17158", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "IMAMURA, Hitoshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "22124", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "MORIMOTO, Kouji", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "22125", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "HASHIMOTO, Keiji", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "22126", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "KAWAI, Satoshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "22127", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Uno, Bunji", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "17924", "nameIdentifierScheme": "WEKO"}]}]}, "item_1_description_1": {"attribute_name": "ページ属性", "attribute_value_mlt": [{"subitem_description": "P(論文)", "subitem_description_type": "Other"}]}, "item_1_description_11": {"attribute_name": "抄録(日)", "attribute_value_mlt": [{"subitem_description": "Melatoninおよびその関連化合物のtrifluoroacetyl(TFA)化反応によって生成する3,3-spirocyclicインドール誘導体の生成機構を考察した。Melatonin,melatonin-(N-acetyl)-d_3,serotonin類およびtryptamine類のTFA誘導体のマススペクトルの測定とその解析より,この特異的な誘導体化反応は側鎖にエノール化しうるN-acyl基をもつN-acyltryptamine類に共通して起こる閉環反応であることを明らかにした。そして,インドール骨格のN-TFA化による3位の活性化と側鎖のN-acyl基のエノール化を経てspirocyclic構造生成に至るmelatoninのTFA誘導体反応の生成機構が提唱された。", "subitem_description_type": "Other"}]}, "item_1_description_12": {"attribute_name": "抄録(英)", "attribute_value_mlt": [{"subitem_description": "The trifluoroacetylation (TFA) mechanism of melatonin was extensively discussed on the basis of mass spectral data for the TFA derivatives of melatonin, melatonin-(N-acetyl)-d_3,serotonins, and tryptamines. It has been demonstrated that 3,3-spirocyclic indole derivatives are commonly generated in the TFA reactions of N-acyltryptamines of the enolic form. We have proposed a mechanism where the specific cyclization reaction involving the spirocyclic structure proceeds by virtue of activation of the 3-position of the indole moiety induced by TFA of the N atom in the moiety and enolation of the N-acyl group.", "subitem_description_type": "Other"}]}, "item_1_source_id_13": {"attribute_name": "雑誌書誌ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00053514", "subitem_source_identifier_type": "NCID"}]}, "item_1_text_10": {"attribute_name": "著者所属(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "Laboratory of Pharmaceutical Analytical Chemistry, Gifu Pharmaceutical University/Laboratory of Pharmaceutical Analytical Chemistry, Gifu Pharmaceutical University/Laboratory of Pharmaceutical Analytical Chemistry, Gifu Pharmaceutical University/Kyoto Pharmaceutical University/Laboratory of Pharmaceutical Analytical Chemistry, Gifu Pharmaceutical University/Laboratory of Pharmaceutical Analytical Chemistry, Gifu Pharmaceutical University"}]}, "item_1_text_9": {"attribute_name": "著者所属(日)", "attribute_value_mlt": [{"subitem_text_value": "岐阜薬科大学/岐阜薬科大学/岐阜薬科大学/京都薬科大学/岐阜薬科大学/岐阜薬科大学"}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2001-06-30"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00000074073.pdf", "filesize": [{"value": "396.2 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 396200.0, "url": {"url": "https://gifu-pu.repo.nii.ac.jp/record/12168/files/KJ00000074073.pdf"}, "version_id": "54eb1702-6f32-468b-a45b-793b1863db5f"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "\u003c一般論文\u003eMelatoninのtrifluoroacetyl誘導体の生成機構に関する考察", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "\u003c一般論文\u003eMelatoninのtrifluoroacetyl誘導体の生成機構に関する考察"}, {"subitem_title": "\u003cRegular Article\u003eMechanistic Study on Generation of the Trifluoroacetyl Derivative of Melatonin", "subitem_title_language": "en"}]}, "item_type_id": "1", "owner": "5", "path": ["197"], "permalink_uri": "https://gifu-pu.repo.nii.ac.jp/records/12168", "pubdate": {"attribute_name": "公開日", "attribute_value": "2001-06-30"}, "publish_date": "2001-06-30", "publish_status": "0", "recid": "12168", "relation": {}, "relation_version_is_last": true, "title": ["\u003c一般論文\u003eMelatoninのtrifluoroacetyl誘導体の生成機構に関する考察"], "weko_shared_id": 5}